Anthropic internal model generates 17 scorpion toxin binders meeting criteria from 211 lab-tested designs

·2026.11.01 15:53

Key point

An internal Anthropic research model generated 318,484 protein designs, of which 17 lab-tested candidates met criteria for binding scorpion neurotoxins.

Details

  • Citrini Research, a financial investment research firm, engaged Anthropic to test if Claude could help non-experts design binders for scorpion neurotoxins, with the goal of developing an antivenom.
  • An internal research model operated autonomously for 64 hours with four follow-up prompts, generating 318,484 protein designs and selecting 180 candidates.
  • The team added 31 more designs with Claude's assistance, resulting in 211 total designs that were lab-tested by Adaptyv Bio and Twist Bioscience.
  • 17 of the 211 designs met Anthropic's criteria for a binder, though Anthropic notes it has not confirmed they neutralize venom in a cellular environment.
  • Anthropic is releasing all 211 designs and the associated data.

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